منابع مشابه
The role of protein C deficiency in the etiology of Perthes disease.
BACKGROUND Recent reports support the hypothesis that thrombophilia plays an important role in the pathogenesis of Perthes disease (PD) and the objective of this report is to show evidence of the role of protein C deficiency in the etiology of PD, based on a meta-analysis of current scientific literature. MATERIAL AND METHODS Studies were selected in all languages over the last twenty years (...
متن کاملRemarks on the etiology and pathogenesis of Perthes' disease: an experiment-based hypothesis.
The literature on Perthes' disease points up the significance of specific anatomical conditions affecting vascularization of the femoral head, as well as immaturity and mechanical weakening of the bone tissue in the etiology and pathogenesis of this disorder in children. An experimental study using calf femurs as models confirmed the author's hypothesis that the areas most susceptible to mechan...
متن کاملPerthes' disease.
This is one of a series of occasional articles highlighting conditions that may be more common than many doctors realise or may be missed at first presentation. The series advisers are Anthony Harnden, professor of primary care, Nuffield Department of Primary Care Health Sciences, University of Oxford, and Richard Lehman, general practitioner, Banbury. To suggest a topic, please email us at pra...
متن کاملThe pathogenesis of Perthes' disease.
It has been shown that in the puppy, two infarcts separated by an interval of four weeks produce a disorder of long duration which results in flattening and broadening of the femoral head and which reproduces the radiological changes seen in Perthes' disease in man. The histological appearances produced by two infarcts are characteristic. In this study the histological appearance of fifty-seven...
متن کاملPerthes' disease of the hip.
It is now sixty years since Legg (1910), Calve (1910) and Perthes (1910) described the condition of coxa plana, or Perthes’ disease as it is more often called today, thus allowing its differentiation from the much more serious tuberculosis of the hip with which it had formerly been confused. It is ironical to find all these years later that a diagnosis of tuberculosis nowadays entails no more t...
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ژورنال
عنوان ژورنال: Journal of the American Medical Association
سال: 1917
ISSN: 0002-9955
DOI: 10.1001/jama.1917.02590460024005